The science behind CBD topicals.

Jul 9th 2020

The science behind CBD topicals.

CBD products come in different concentrations and formulations that allow users to have an excellent experience regardless of age, location, or health status. These CBD products are divided into 4 main categories; edibles, topicals, and breathables. These classes of CBD products have their unique route of application, bioavailability, and target organs/tissues they act on. While CBD edibles are applied via the oral route, breathables come in handy as vapes and e-cigs. In this article, we shall explore the science behind CBD topicals, their mode of activity, and possible pros and cons to consider.


CBD topicals come in the form of CBD balms, CBD creams, lotions, and other skincare products that were specially designed for direct application on the skin hence the name; topicals.

Just like every other CBD product, CBD topicals are made from the combination of different chemicals, including cannabinoids (like CBD, CBG, CBC, CBN, and THC), terpenes and essential oils. Since the skin is richly supplied with cannabinoid receptors, applying CBD topicals to the skin helps to promote its absorption and activity in the body.

How CBD topicals work

All CBD products need to react with endocannabinoid receptors (CB1 and CB2) to produce their effect. While the CB1 receptors are found in the brain and peripheral organs like the liver, the CB2 receptors are great at modulating the effect of the immune system.

Once CBD topicals are applied to the affected region, it can penetrate the skin via the subdermal and dermal skin layers to access the receptors. It is pertinent to note that the endocannabinoid system (ECS) controls cognitive activities such as hunger, pleasure, and pain. Once CBD is present in circulation, it binds to the cell receptors present in the skin.

Information from research has shown how phytocannabinoids like CBD can interact with the ECS receptors, and other enzyme-catalyzed processes within the skin to modulate pain and inflammation. There are reports on how CBD topicals can assist people suffering from psoriasis, acne, and eczema.

What are the Benefits of using topical CBD?

Topical CBD can interact with the ECS receptors in the skin to alleviate skin problems, inflammations, and pain in the affected area. Since the rate of absorption is high, it is highly recommended that rubbing a small portion of the CBD product can produce excellent relief.

Information from research published in 2017 shows how the use of topical treatments can reduce acute joint inflammation in rats. Another study published in the same year showed how the use of topical CBD could provide relief from psoriasis and contact dermatitis.


Topical CBD products are great at providing relief for skin-related conditions. They have a high level of absorption and interaction with the ECS receptors. Topical CBD product offers a high level of bioavailability and is safe for all ages.

Don’t forget to contact us if you have questions about the use of topical CBD and its application in many conditions. We will love to hear from you soon.